Depresh Mode with John Moe
Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and more laughs than you might expect.
Latest Episode
A Holiday Family Survival Mini-sode (25.11.2025)
Previous Episodes
- Esmé Weijun Wang’s Mind Convinced Her She Was Dead and In the Afterlife
- Is Your Mental Health Diagnosis an Identity or Something More Meaningless?
- The Personal Side of Huge Cuts to Addiction, Suicide Prevention, and Mental Health Programs
- Seasonal Affective Disorder and Why It Sucks So Bad
- Is Whiteness a Mental Health Problem? Dr. Jonathan Mathias Lassiter Thinks So.
- Is the U.S. Government Going To Take Away Your Antidepressants?
- P.E. Moskowitz on Whether Your Mind is Broken or the World Is
- Kendall Toole Gets Knocked Down, Never Knocked Out
- Bruce Springsteen as Over-The-Counter Depression Treatment
- Emma Swift Had a Complete Mental Breakdown. Found Health. Made Music About It.
- Sycophantic Chatbots and Alarming Cases of “AI Psychosis”
- Alex Edelman on ADHD, Grief, Infiltrating White Nationalists, and The Paper
- Better Home Design for Better Mental Health with Dr. Beverly Walpole
- Denise Winkelman: Comedian/Trans Woman/Former Pro Wrestler/Chronic Pain Sufferer
- Ashly Burch Delivers Mental Health Insight Using Puppets and Swear Words
- Author/Comedian Tiffany Jenkins on Anxiety, Addiction, Felonies, Success, and Not Wanting to Exist
- We Have Two Guests This Week: Comedian Aaron Foster and His Depression
- Nurse Blake on Gay Conversion Therapy, Panic Attacks, and, Well, Nursing
- Gavin Rossdale of Bush on Loss, Xanax, and New Emotional Landscapes
- Insomnia and Mental Health Problems: Each Horrible, Each Feeding the Other
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