Depresh Mode with John Moe
Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and more laughs than you might expect.
Latest Episode
A.J. Daulerio on Bipolar, Substances, Depression, Suicide, and the Psychic Weight of Hulk Hogan (11.01.2026)
Previous Episodes
- Two Truths To Make 2026 a Better Mental Health Year
- Mike Doughty Was Recently Hospitalized for Depression Twice. It Helped.
- Tom Johnson Advised LBJ, Ran CNN, and Drove Himself to Severe Depression
- Anger: Let’s Talk About It, Learn About It, Not Fear It, Use It For Good
- Unemployment Hurts Mental Health, Horror Movies Might Help It. Really!
- Maureen Johnson Became Friends with Her Anxiety Monster
- A Holiday Family Survival Mini-sode
- Esmé Weijun Wang’s Mind Convinced Her She Was Dead and In the Afterlife
- Is Your Mental Health Diagnosis an Identity or Something More Meaningless?
- The Personal Side of Huge Cuts to Addiction, Suicide Prevention, and Mental Health Programs
- Seasonal Affective Disorder and Why It Sucks So Bad
- Is Whiteness a Mental Health Problem? Dr. Jonathan Mathias Lassiter Thinks So.
- Is the U.S. Government Going To Take Away Your Antidepressants?
- P.E. Moskowitz on Whether Your Mind is Broken or the World Is
- Kendall Toole Gets Knocked Down, Never Knocked Out
- Bruce Springsteen as Over-The-Counter Depression Treatment
- Emma Swift Had a Complete Mental Breakdown. Found Health. Made Music About It.
- Sycophantic Chatbots and Alarming Cases of “AI Psychosis”
- Alex Edelman on ADHD, Grief, Infiltrating White Nationalists, and The Paper
- Better Home Design for Better Mental Health with Dr. Beverly Walpole
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